![]() While not as strong as the Memory Index (area under the curve = 0.66) in predicting conver sion to AD, Julaynont et al. Conversion to AD was 90.5% in patients with scores below the cutoff for impairment on both the total score (< 20/30 points) and the Memory Index Score (< 7/15 points), 74.5% when 1 score was below the cutoff, and 53% when both scores were above the cutoff. The investigators found that both the traditional total score and the Memory Index Score, consisting of the performance on delayed free, cued, and recognition conditions of the word list, were strong predictors of conversion from mild cognitive impairment (MCI) to Alzheimer disease (AD) over an average follow-up of 18 months. developed MoCA index scores for the domains of memory, executive function, visuospatial function, language, attention, and orientation. Traditional interpretation of the MoCA is based upon the summed points across all items, with a maximum of 30 points. The Montreal Cognitive Assessment (MoCA) is a popular test used for cognitive screening in dementia clinics. A combined score has stronger incremental validity than the individual index scores. Conclusion: Administration of the entire MoCA is more informative than the index scores, especially in distinguishing normal cognition versus MCI. A combined score incorporating the Memory, Executive, and Orientation indexes also improved incremental validity for all 3 group comparisons. Results: Effect sizes for the total score were large (> 0.80) and exceeded the index scores in differentiating those with MCI versus normal cognition, MCI versus AD, and AD versus normal cognition. ![]() Methods: Effect sizes were calculated for Alzheimer’s Disease Neuroimaging Initiative research participants with normal cognition ( n = 295), MCI ( n = 471), or AD ( n = 150). Background/Aims: The aim of this paper was to evaluate the incremental validity of the Montreal Cognitive Assessment (MoCA) index scores and the MoCA total score in differentiating individuals with normal cognition versus mild cognitive impairment (MCI) or Alzheimer disease (AD). ![]()
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